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『簡體書』合成生物学:伦理风险与治理对策(英文版)

書城自編碼: 4083686
分類:簡體書→大陸圖書→自然科學生物科學
作者: 雷瑞鹏
國際書號(ISBN): 9787577212371
出版社: 华中科技大学出版社
出版日期: 2025-02-01

頁數/字數: /
書度/開本: 32开 釘裝: 平装

售價:HK$ 108.9

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編輯推薦:
《合成生物学:科学、伦理与治理》一书是一本综合性的著作,旨在向读者展示合成生物学在科学研究中的最新进展和主要特点,通过结合合成生物学的实践,从医药、农业、环境等领域分别阐述合成生物学的伦理争议,对比各国的治理方案和政策方针,并提出合成生物学的伦理治理框架。本书即具有学术的前沿性,也具有科普上的传播性。
內容簡介:
合成生物学作为认识生命的“钥匙”、改变未来的颠覆性技术,打开了从非生命物质向生命物质转化的大门,实现生命体系的理性设计与编辑,为生命科学研究提供了新范式,促进生物技术迭代发展,成为未来生物产业发展的驱动力。经过20余年的发展,合成生物学领域已取得系列突破,创新应用逐步实现。近年合成生物学的快速发展也带来了许多伦科学、伦理和治理上的问题和挑战。在科学的维度,合成生物学从生物技术、生物工程学科逐步过渡到现在的形态,其科学特征以及学科体系的基础仍需要进一步说明和澄清。在伦理和治理上,合成生物学的发展和应用引起许多决策者和利益相关方的关切,如是否应该合成生命系统、合成生物学是否会带来分配的不公正、是否有适当的制度来管理这些技术,以及公众如何、何时参与这些决策。《合成生物学:科学、伦理与治理》从合成生物学的学科特征及其发展态势、合成生物学中的重要伦理问题及治理方案和合成生物学的伦理治理框架等方面进行了阐述。
關於作者:
电子科技大学马克思主义学院教授/博导,科技伦理治理研究中心主任。2019年5月9日在国际*科学期刊Nature发表国内人文学科领域第一篇研究论文“Reboot Ethics Governance in China”(《重建中国的伦理治理》),在国内首次提出“科技伦理治理”和“伦理先行”概念,并系统阐述科技伦理治理基本原则,相关概念和原则已被系列中央文件和两办《关于加强科技伦理治理意见》采纳。生命伦理学创始研究机构Hastings中心Fellow,中国自然辨证法研究会理事,中国伦理学会常务理事。
目錄
ContentsPART ⅠEthical Debates on Synthetic Biology1An Analysis of the “Playing God” Argument against Synthetic Biology1.1Introduction1.2The Origin of “Playing God” Argument1.3The Interpretation of the Expression of Playing God1.4The Debate on Whether Synthetic Biology “Plays God”1.5Deficiencies of “Playing God” as an Argument1.6References2Some Remarks on the Argument Appealing to Nature against Synthetic Biology2.1Introduction2.2The Argument Appealing to Nature against Synthetic Biology and an Analysis of Its Deficiencies2.3Ambiguity of the Concept Nature2.4Problems in the Morally Significant Line between the Natural and the Non/Unnatural2.5Allegations to Synthetic Biology Stemming from Argument Appealing to Nature2.6Conclusion2.7References3On the Biocentrist Argument against Synthetic Biology3.1Introduction3.2Biocentrism and Its Advocates: A Critique of Synthetic Biology3.3Argument Appealing to Natural Evolutionary History3.4Argument Appealing to Teleological Organization3.5Argument Appealing to the Good of Own or Interests3.6References4Research on Responsibility Ethics of DNA Synthesis Technology4.1Introduction4.2Ethics of Responsibility of Hans Jonas4.3The Necessity of Applying Ethics of Responsibility in DNA Synthesis Techniques4.4Application of Ethics of Responsibility in the Practice of DNA Synthesis Technology4.5Suggestions for Applying Ethics of Responsibility in the Practice of DNA Synthesis Technology4.6Conclusion4.7References5Analysis of Ethics Dumping and Proposed Solutions in the Field of Biomedical Research in China5.1Introduction5.2The Definition of Ethics Dumping5.3Typical Cases of Ethics Dumping in Biomedical Research in China5.4Analysis of the Causes of Ethics Dumping in Biomedical Research in China5.5Policy Recommendations5.6ReferencesPART ⅡRisk Analysis in Synthetic Biology6Safety Risks and Ethical Governance of Biomedical Applications of Synthetic Biology6.1Introduction6.2The Biomedical Applications of Synthetic Biology6.3An Analysis of the Safety Risks of the Application of Synthetic Biology within Biomedicine6.4Ethical Considerations in the Application of Synthetic Biology within the Biomedical Field6.5Recommendations for Ethical Governance of Biomedical Applications of Synthetic Biology6.6Conclusion6.7References7Risks and Governance Recommendation for Synthetic Virus Technology from an Ethical Perspective7.1Introduction7.2Synthetic Virus Technology and Kinds of Risks7.3Challenges Faced by Existing Risk Governance Strategies7.4Governance Recommendations for Synthetic Virus Technology7.5Conclusion7.6References8Ethical Perspective on the Risk Assessment and Prospective Governance of Synthetic Biofuels8.1Introduction8.2Risk Assessment and Ethical Issues of Synthetic Biofuels8.3Prospective Governance of Synthetic Biofuels from an Ethical Perspective8.4Conclusion8.5References9Challenges and Principled Responses to Privacy Protection from Biometric Technology in China9.1Introduction9.2The Definition of Biometric Technology and Biometric Characteristics9.3The Challenges of Biometric Technology for Privacy Protection9.4Principled Responses to Privacy Protection from Biometric Technology9.5Conclusion9.6ReferencesPART ⅢGovernance Countermeasures in Synthetic Biology10Ethical Framework on Risk Governance of Synthetic Biology10.1Introduction10.2The Relationship between Environmental Risk and Synthetic Biology10.3Methods for Environmental Risk Assessment of Synthetic Biology10.4Ethical Principles in Environmental Risk Governance10.5Conclusion10.6References11Establishing a Management Framework for Biosafety Risk Assessments of Synthetic Biology11.1Introduction11.2Synthetic Biology Enabling Technology11.3Biosafety Risk Assessments of Synthetic Biology11.4Framework for Biosafety Risk Assessments11.5Discussion11.6Summary11.7References12Risks and Countermeasures of LaboratoryAcquired Infection Based on Pathogen Transmission Routes12.1Introduction12.2LAI Risk Analysis Based on Transmission Routes12.3Response to LAIs with Different Transmission Routes12.4Comprehensive Strategy12.5Conclusion12.6References13Regulation and Management of the Biosecurity for Synthetic Biology13.1Introduction13.2Biosecurity Risks of Synthetic Biology13.3Situation of the Regulation and Management of Biosecurity for Synthetic Biology in the International Community13.4Situation of the Regulation and Management of Biosecurity for Synthetic Biology in China13.5Suggestions on the Regulation and Management of Biosecurity for Synthetic Biology in China13.6Conclusion13.7References14Can Synthetic Biological Products Be Applied to the Cartagena Protocol on Biosafety 14.1Introduction14.2Progress in the Negotiation of Synthetic Biology under the Framework of the CBD14.3Application of Synthetic Biological Products under the Rules of the Biosafety Protocol14.4Conclusion14.5References15A Leap of Faith: Building the Trust in Human Biobanks15.1Introduction15.2Theoretical Foundations of Public Trust in HBs: A Leap of Faith15.3Is There a Universal Formula for the Construction of Public Trust in HBs 15.4Schemes for the Establishment and Reinforcement of Public Trust in HBs15.5Conclusion15.6References
內容試閱
ForewordSynthetic biology, as an emerging scientific field, stands at the forefront of scientific innovation, promising unprecedented advancements in our ability to understand, manipulate, and create biological systems.This field holds immense potential to revolutionize medicine, agriculture, energy production, and countless other aspects of human life.However, accompanying these groundbreaking capabilities are significant ethical, safety, and governance challenges that we must address to ensure the responsible development and application of synthetic biology.This book delves into the complex and multifaceted issues arising from this rapidly evolving discipline.It examines the profound ethical questions raised by the ability to design and construct new biological systems not found in nature.What does it mean to “create” life, and what are the ethical limits of manipulating the building blocks of life itself? How can we ensure that the pursuit of scientific progress in synthetic biology aligns with our values and benefits humanity as a whole?Beyond the philosophical considerations, this book tackles the safety and security risks associated with synthetic biology.How can we mitigate the risks of the accidental release of synthetic organisms or their components? How can we safeguard against malicious actors seeking to exploit these technologies for harmful purposes? To address these challenges, we need robust regulatory frameworks, international collaboration, and ongoing dialogue between scientists, policymakers, and the public.Facing the tension between the rapid development of synthetic biology and the ethical and governance challenges it presents, Chinas Ministry of Science and Technology, for the first time in 2018, incorporated research on the ethical and policy framework of synthetic biology into the National Key Research and Development Program.This book is a significant outcome of the project “Research on the Framework of Ethical Governance on Synthetic Biology”(2018YFA0902400). During this project, our team has published a series of research articles on various aspects of synthetic biology ethics and governance.This book builds upon those published findings, offering a comprehensive and systematic analysis of the ethical risks and governance countermeasures in synthetic biology. It aims to provide valuable ethical and governance references for the development of synthetic biology.This book delves into the multifaceted issues that arise from this rapidly evolving discipline. As synthetic biology enables the design and construction of new biological systems not found in nature, it challenges traditional views of life, human status in nature, and the relationship between humans and the natural world.These challenges have sparked intense ethical debates and raised questions about the legitimacy and acceptability of synthetic biology.This book is structured to provide a comprehensive examination of the ethical controversies, risk assessments, and governance strategies pertinent to synthetic biology.It is divided into three main parts.Ethical Debates on Synthetic BiologyThis part explores the philosophical and ethical arguments surrounding synthetic biology, including the contentious “playing God” argument, and appeals to nature argument and biocentrist argument.It critically analyzes these debates and highlights the deficiencies and complexities inherent in these ethical positions.Additionally, this part also explores the application of various ethical theories to synthetic biology, such as grappling with the applicability of responsibility ethics within synthetic biology.Furthermore, the discussion extends to the concerning phenomenon of “ethics dumping” in synthetic biology, highlighting instances where potentially controversial research migrates to regions with more lenient ethical oversight.This critical examination of ethical considerations underscores the books commitment to fostering a holistic understanding of synthetic biology, acknowledging both its vast potential and the complex ethical challenges it presents.Risk Analysis in Synthetic BiologyThe second part of the book focuses on the various risks associated with synthetic biology, especially in environmental, biofuel and biometric technology. It provides a detailed overview of participant safety, biosafety and biosecurity risks, and discusses the principles and practical recommendations for ethical governance, such as assessing the potential risks and benefits of this technology, highlighting the ethical dilemmas associated with its development and deployment, and proposing a governance framework.Governance Countermeasures in Synthetic BiologyThe last part presents an ethical framework for the governance of synthetic biology.It emphasizes the importance of precautionary principles, stakeholder interests, and dynamic riskbenefit assessments.This part also discusses the need for robust biosafety management frameworks and the integration of ethical principles into policy and regulatory measures.By examining these critical aspects, this book aims to provide a balanced and informed perspective on the challenges and opportunities presented by synthetic biology.It seeks to contribute to the ongoing discourse on how to navigate the ethical and governance landscape of this transformative field, ensuring that its development is both innovative and responsible.We hope that this book will serve as a valuable resource for researchers, policymakers, ethicists, and anyone interested in the ethical and governance dimensions of synthetic biology.National Key R&D Program“Research on the Framework of Ethical Governance on Synthetic Biology”(2018YFA0902400) GroupIntroductionSynthetic Biology: Ethical Risks and Governance Countermeasures is structured to provide a comprehensive examination of the ethical controversies,risk assessments,and governance strategies pertinent to synthetic biology. It is divided into three main parts.Part Ⅰ explores the ethical arguments on synthetic biology,including the contentious “playing God” argument, and appeals to nature argument and biocentrist argument. It critically analyzes these debates and highlights the deficiencies and complexities inherent in these ethical positions.Additionally,this part also explores the application of various ethical theories to this rapidly evolving field,such as grappling with the applicability of responsibility ethics within synthetic biology, and questioning the boundaries and limits of accountability when dealing with engineered organisms. Furthermore,the discussion extends to the concerning phenomenon of “ethics dumping” in synthetic biology,highlighting instances where potentially controversial research migrates to regions with more lenient ethical oversight.Part Ⅱ focuses on the various risks associated with synthetic biology,particularly in biomedical applications.It provides a detailed overview of participant safety,biosafety,and biosecurity risks,and discusses the principles and practical recommendations for ethical governance. This part also addresses the risks of the application of synthetic biology,such as the environmental risks posed by synthetic biology,analyzes the limitations of existing risk governance strategies, offers recommendations for the ethical governance of this powerful technology, and explores the ethical considerations surrounding synthetic biofuels.It assesses the potential risks and benefits of this technology, proposes a framework for the prospective governance of synthetic biofuels,emphasizing ethical considerations, and addresses the privacy implications of biometric technology,a field closely intertwined with synthetic biology. It analyzes the challenges posed by biometric technology to privacy protection and proposes principled responses to address these concerns,particularly in the context of China.Part Ⅲ, the final part presents an ethical framework for the governance of synthetic biology. It proposes a principlebased approach to governance in synthetic biology, which emphasizes the importance of precautionary principles,stakeholder interests,and dynamic riskbenefit assessments. Under this framework,this part also discusses the integration of ethical principles into policy and regulatory measures, and the application of the framework in the context of biosafety and biosecurity in synthetic biology. It also analyzes the applicability of the Cartagena Protocol on Biosafety to synthetic biological products.It reviews the progress of international negotiations on this issue within the framework of the Convention on Biological Diversity and discusses its applicability in synthetic biology.By examining these critical aspects, this book aims to provide a balanced and informed perspective on the challenges and opportunities presented by synthetic biology.It seeks to contribute to the ongoing discourse on how to navigate the ethical and governance landscape of this transformative field,ensuring that its development is both innovative and responsible.

 

 

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