_x000c_
XXII
威廉姆斯内分泌学
Contents
Section I: Hormones and Hormone Action
▲
1 Principles of Endocrinology
Shlomo Melmed， Richard J. Auchus， Allison B. Goldfine， Ronald J. Koenig，
Clifford J. Rosen， P. Reed Larsen， Kenneth S. Polonsky， and Henry M.
Kronenberg 2
2 Principles of Hormone Action
Evan D. Rosen and Christin Carter-Su 13
3 Genetics of Endocrinology
Robert L. Thomas， Joel N. Hirschhorn， and Amit R. Majithia 42
4 Laboratory Techniques for Recognition of Endocrine Disorders
Patrick M. Sluss and Frances J. Hayes 62
5 The Global Burden of Endocrine Diseases
Maria Inês Schmidt， Laercio J. Franco， Ewerton Cousin， and Bruce B.
Duncan 91
6 Navigating Through Clinical Practice Guidelines in
Endocrinology
Naykky Singh Ospina， Spyridoula Maraka， Rene Rodriguez-Gutierrez， Juan
P. Brito， and Victor Montori 103
Section II: Hypothalamus and Pituitary
7 Neuroendocrinology
Ronald M. Lechan 114
8 Pituitary Physiology and Diagnostic Evaluation
Ursula Kaiser and Ken Ho 184
9 Pituitary Masses and Tumors
Shlomo Melmed 236
10 Posterior Pituitary
Christopher J. Thompson and Joseph G. Verbalis 303
Section III: Thyroid
11 Thyroid Pathophysiology and Diagnostic Evaluation
Domenico Salvatore， Ronald Cohen， Peter A. Kopp， and P. Reed Larsen 332
12 Hyperthyroid Disorders
Anthony Hollenberg and Wilmar M. Wiersinga 364
13 Hypothyroidism and Thyroiditis
Gregory A. Brent and Anthony P. Weetman 404
14 Nontoxic Diffuse Goiter， Nodular Thyroid Disorders， and Thyroid
Malignancies
Sebastiano Filetti， R. Michael Tuttle， Sophie Leboulleux， and Erik K.
Alexander 433
Section IV: Adrenal Cortex and Endocrine Hypertension
15 The Adrenal Cortex
John D.C. Newell-Price and Richard J. Auchus 480
16 Endocrine Hypertension
William F. Young， Jr. 542
Section V: Sexual Development and Function
17 Physiology and Pathology of the Female Reproductive Axis
Serdar E. Bulun 574
18 Hormonal Contraception
Rebecca H. Allen， Andrew M. Kaunitz， Martha Hickey， and Annabelle
Brennan 642
19 Testicular Disorders
Alvin M. Matsumoto and Bradley D. Anawalt 668
20 Sexual Dysfunction in Men and Women
Shalender Bhasin and Rosemary Basson 756
21 Transgender Endocrinology
Stephen M. Rosenthal and Vin Tangpricha 796
Section VI: Endocrinology and the Life Span
Section VI A: Maternal-Fetal
22 Endocrine Changes in Pregnancy
Joshua F. Nitsche， Glenn D. Braunstein， and Sarah L. Berga 808
23 Endocrinology of Fetal Development
Harshini Katugampola， Evelien F. Gevers， and Mehul T. Dattani 825
Section VI B: Childhood
24 Disorders of Sex Development
Yee-Ming Chan， Sabine E. Hannema， John C. Achermann， and Ieuan A. Hughes 867
25 Normal and Aberrant Growth in Children
David W. Cooke， Sara A. DiVall， and Sally Radovick 937
26 Physiology and Disorders of Puberty
Dennis M. Styne 1023
Section VI C: Adult
27 Hormones and Athletic Performance
Fabio Lanfranco， Ezio Ghigo， and Christian J. Strasburger 1165
28 Endocrinology and Aging
Annewieke W. van den Beld and Steven W.J. Lamberts 1179
Section VII: Mineral Metabolism
29 Hormones and Disorders of Mineral Metabolism
F. Richard Bringhurst， Marie B. Demay， and Henry M. Kronenberg 1196
30 Osteoporosis: Basic and Clinical Aspects
Francisco J. A. de Paula， Dennis M. Black， and Clifford J. Rosen 1256
31 Rickets and Osteomalacia
Arti Bhan， Ajay D. Rao， Sanjay K. Bhadada， and Sudhaker D. Rao 1298
32 Kidney Stones
David A. Bushinsky 1318
Section VIII: Disorders of Carbohydrate and Fat Metabolism
33 Physiology of Insulin Secretion
Ele Ferrannini and Andrea Mari 1338
34 Pathophysiology of Type 2 Diabetes Mellitus
C. Ronald Kahn， Heather A. Ferris， and Brian T. O’Neill 1349
35 Therapeutics of Type 2 Diabetes Mellitus
Matthew C. Riddle and Andrew J. Ahmann 1371
36 Type 1 Diabetes Mellitus
Mark A. Atkinson， Dayna E. McGill， Eyal Dassau， and Lori Laffel 1403
37 Complications of Diabetes Mellitus
Michael Brownlee， Lloyd P. Aiello， Jennifer K. Sun， Mark E. Cooper， Eva L.
Feldman， Jorge Plutzky， and Andrew J. M. Boulton 1438
38 Hypoglycemia
Philip E. Cryer and Ana María Arbeláez 1525
39 Neuroendocrine Control of Energy Stores
Martin G. Myers， Jr.， and David P. Olson 1552
40 Obesity
Eleftheria Maratos-Flier 1567
41 Disorders of Lipid Metabolism
Clay F. Semenkovich and Ira J. Goldberg 1581
Section IX: Polyendocrine and Neoplastic Disorders
42 Multiple Endocrine Neoplasia
Paul J. Newey and Rajesh V. Thakker 1622
43 The Immunoendocrinopathy Syndromes
Jennifer M. Barker， Peter A. Gottlieb， and Mark S. Anderson 1658
44 Endocrinology of HIV/AIDS
Todd T. Brown and Steven K. Grinspoon 1672
45 Neuroendocrine Tumors and Related Disorders
Kjell .berg 1691
46 Managing Reproductive Disorders in Cancer
Mahmoud Salama， Victoria Sandler， and Teresa K. Woodruff 1710
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